The area under the curve (AUC) was 0.880 with the sensitivity of 84.0%, and specificity of 80.4% to distinguish PC. Patients with PC exhibited markedly higher preoperative serum CXCL5 levels compared with that in healthy individuals ( P<0.001). Our initial analysis identified CXCL5 as a cancer-related gene highly expressed in PC.
Chemokine (C-X-C motif) ligand 5 is an important regulator of tumor progression in many cancers, and could serve as potential serum cancer biomarker.
